Interview with Niccolò Cosottini (DC10)

Interview with our Doctoral Candidate (DC10) Niccolò Cosottini, on his PhD at University of York, under the supervision of Prof. David K. Smith. 

First of all, can you tell us more about yourself? Where are you from, what are your hobbies?

I’m Niccolò, I grew up in a village in Tuscany. When I’m not doing science I enjoy reading about politics, philosophy and learning languages. To balance the nerdy stuff I practice tricking–it sounds weird but it’s just an underground sport that mixes martial arts and acrobatics.

And your university background?

I completed a bachelor degree in chemistry at the university of Florence. I then moved to “Advanced Molecular Sciences” (i.e chemistry in English) for my master’s degree. My research there focused on fabrication and characterization of soft materials.

Why did you choose this career path? What is your interest about science?

I have been interested in science since I was a kid–there is something satisfying about understanding the mechanisms and rules behind physical phenomena. I realized that a PhD would’ve been the best way for me to keep together the search for understanding and a job.

Can you tell us more about your research project?

My research project focuses low molecular weight gelators (LMWGs)– specifically sugar derived LMWGs such as 1,3:2,4-Dibenzylidene-d-sorbitol (DBS). I’m investigating gels at different length-scales as drug delivery systems

Same question, but for people who don’t understand a thing about chemistry (#MultiSMARTfordummies)

We rely on medicine to get well, but because most drugs travel through our entire bloodstream to reach a single target, they often cause unwanted side effects. My research focuses on making treatment more efficient by using « drug delivery systems. » They can be considered small shuttles that carry the medication directly to where it’s needed. By hitting the target precisely, we can use a much smaller dose and keep the rest of the body safe from side effects. These « shuttles » are actually made of gels. They are structurally similar to the hair gels or gelatin we use every day—they’re just designed to do something different.

What will your research bring to people and to society in general?

Drug delivery is a broad and complex field. Most of the systems which are developed fail at one the many steps in between basic research and regulatory approval. Success rate is low, but when an invention works it helps all the people who need treatments. My research will add one piece of the puzzle to this area but it is unlikely that it will ever reach the market.

How do you feel being part of a MSCA Doctoral Network project?

I feel that being part of a MSCA Doctoral Network project is a great opportunity from both a personal and professional perspective. I have met new friends who are also great scientists. I have done science in varied environments and travelled to different countries. The project makes you grow as a scientist and as a person. 

What are your projects after the defense  of your thesis?

I would like to continue my journey in academia with a postdoc. I enjoy the freedom to try new things and the flexibility of this environment.

If there is one thing that I have learnt during my PhD though,  it’s that you never know anything for sure. Now I’m saying this, but I might change my mind in the future

Do you have a recommendation/an advice for future potential MSCA fellows?

Enjoy the journey, try new things, embrace challenges and more importantly take care of yourself

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